(= DNA photolyase)
Family of ubiqitous enzymes found in bacteria, archaebacteria and eukaryotes that can repair UV-induced DNA damage. The protein (between 454 to 614 residues) is associated with two prosthetic groups, FADH and a light-harvesting cofactor, MTHF (5,10-methenyltetrahydofolyl polyglutamate). Light is needed for the repair step.

Dictionary of molecular biology. 2004.

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  • Photolyase — is an enzyme that binds complementary DNA strands and breaks certain types of pyrimidine dimers that are caused by exposure to ultraviolet light. Two kinds of pyrimidine dimers arise when a pair of thymine bases or cytosine bases on the same… …   Wikipedia

  • Photolyase — FADH2 (jaune) et 8 HDF (cyan). La photolyase est une enzyme qui répare certains des dommages causés dans l ADN par les ultraviolets et en particulier les dimères de thymine ou plus généralement de pyrimidine. La protéine agit sous l action d une… …   Wikipédia en Français

  • photolyase — noun An enzyme that repairs DNA that has been damaged by light …   Wiktionary

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  • DNA photolyase — Identifiers Symbol DNA photolyase Pfam PF00875 InterPro …   Wikipedia

  • deoxyribodipyrimidine photolyase — An enzyme in yeast that is activated by light, whereupon it can reverse a previous photochemical reaction by cleaving the cyclobutane ring of the thymine dimer. SYN: dipyrimidine photolyase, photoreactivating enzyme …   Medical dictionary

  • dipyrimidine photolyase — SYN: deoxyribodipyrimidine photolyase …   Medical dictionary

  • Photolyasen — Photolyase Kristallstruktur …   Deutsch Wikipedia

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  • Cryptochrome — 1 (photolyase like) Crystal structure of the PHR domain of cryptochrome 1 from Arabidopsis thaliana.[1] …   Wikipedia

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